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MUS81 protein (Candida glabrata) - STRING interaction network
"MUS81" - Hypothetical protein in Candida glabrata
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
MUS81Hypothetical protein; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5’-end at the branch nick. Typical substrates include 3’- flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI) (By similarity) (628 aa)    
Predicted Functional Partners:
XP_448789.1
Hypothetical protein (223 aa)
     
  0.963
XP_448791.1
Hypothetical protein (1371 aa)
     
  0.963
XP_447490.1
Hypothetical protein (383 aa)
     
  0.903
XP_446832.1
Hypothetical protein (718 aa)
     
  0.877
XP_448123.1
Hypothetical protein (1071 aa)
     
  0.865
XP_445274.1
Hypothetical protein (648 aa)
     
  0.865
EME1
Hypothetical protein; Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5’-end at the branch nick. Typical substrates include 3’- flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI) (By similarity) (580 aa)
       
  0.860
XP_447432.1
Hypothetical protein (942 aa)
     
  0.856
RAD52
Hypothetical protein; Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single- stranded DNA and by stimulation of the RAD51 recombinase (By similarity) (505 aa)
       
  0.852
XP_446331.1
Hypothetical protein (992 aa)
     
  0.848
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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