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BUR2 protein (Candida glabrata) - STRING interaction network
"BUR2" - Hypothetical protein in Candida glabrata
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second shell of interactors
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proteins of unknown 3D structure
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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BUR2Hypothetical protein; Component of the BUR kinase complex involved in transcription regulation. This complex phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric- associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase. The kinase activity of the complex requires the presence of BUR2. Overexpression of BUR2 interferes with mitotic chromosome segregation (By similarity) (357 aa)    
Predicted Functional Partners:
BUR1
Hypothetical protein; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin- conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity) (667 aa)
       
  0.935
XP_445501.1
Hypothetical protein (553 aa)
       
 
  0.685
SET2
Hypothetical protein; Histone methyltransferase that methylates histone H3 to form H3K36me. Involved in transcription elongation as well as in transcription repression (By similarity) (716 aa)
       
 
  0.556
XP_447999.1
Hypothetical protein (349 aa)
       
 
  0.478
XP_445546.1
Hypothetical protein (313 aa)
       
 
  0.476
SPT4
Hypothetical protein; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre- mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity) (102 aa)
       
 
  0.440
XP_447246.1
Hypothetical protein (307 aa)
           
  0.438
PHO85
Hypothetical protein; When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression (302 aa)
       
  0.433
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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