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MSH3 protein (Candida glabrata) - STRING interaction network
"MSH3" - Hypothetical protein in Candida glabrata
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
MSH3Hypothetical protein; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a t [...] (1025 aa)    
Predicted Functional Partners:
XP_447585.1
Hypothetical protein; Component of the post-replicative DNA mismatch repair system (MMR) (957 aa)
   
0.988
XP_445490.1
Hypothetical protein; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (258 aa)
     
  0.978
XP_446304.1
Hypothetical protein (723 aa)
 
  0.970
XP_447944.1
Hypothetical protein (907 aa)
   
  0.942
XP_444920.1
Hypothetical protein (679 aa)
   
  0.920
POL2
Hypothetical protein; DNA polymerase II participates in chromosomal DNA replication (2217 aa)
     
  0.920
XP_449431.1
Hypothetical protein (736 aa)
   
  0.912
XP_446650.1
Hypothetical protein (1454 aa)
     
 
  0.900
XP_446716.1
Hypothetical protein; Component of the post-replicative DNA mismatch repair system (MMR) (1216 aa)
   
 
 
0.881
RFA1
Hypothetical protein (627 aa)
     
  0.875
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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