STRINGSTRING
ERG11 protein (Candida glabrata) - STRING interaction network
"ERG11" - Hypothetical protein in Candida glabrata
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERG11Hypothetical protein; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4’-dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity) (533 aa)    
Predicted Functional Partners:
XP_448182.1
Hypothetical protein (733 aa)
     
  0.992
XP_447380.1
Hypothetical protein (437 aa)
   
  0.992
XP_448420.1
Hypothetical protein (308 aa)
     
 
  0.969
ERG1
Hypothetical protein; Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway (489 aa)
     
 
  0.958
ERG3
Hypothetical protein; Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. May contribute to the regulation of ergosterol biosynthesis (364 aa)
     
 
  0.953
ERG9
Hypothetical protein; Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol (443 aa)
 
 
  0.953
ERG6
Hypothetical protein; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol (372 aa)
   
 
  0.943
LYS2
Hypothetical protein; Catalyzes the activation of alpha-aminoadipate by ATP- dependent adenylation and the reduction of activated alpha- aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate (1374 aa)
     
  0.943
XP_446390.1
Hypothetical protein (349 aa)
   
  0.932
ERG2
Hypothetical protein (224 aa)
     
 
  0.917
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
Server load: low (16%) [HD]