STRINGSTRING
XP_446017.1 protein (Candida glabrata) - STRING interaction network
"XP_446017.1" - Hypothetical protein in Candida glabrata
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
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Experiments
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Textmining
[Homology]
Score
XP_446017.1Hypothetical protein (359 aa)    
Predicted Functional Partners:
XP_445707.1
Hypothetical protein (2090 aa)
     
  0.969
XP_445324.1
Hypothetical protein (478 aa)
     
  0.967
XP_449500.1
Hypothetical protein (364 aa)
       
  0.952
XP_447395.1
Hypothetical protein (191 aa)
     
  0.903
XP_448817.1
Hypothetical protein (803 aa)
     
  0.844
XP_445473.1
Hypothetical protein (548 aa)
     
  0.844
XP_447839.1
Hypothetical protein (620 aa)
     
  0.829
PAN2
Hypothetical protein; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein PAB1, which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome- mediated 3’-5’ exonucleolytic degradation, or deadenlyation- dependent mRNA decaping and subsequent 5’-3’ exonucleolytic degradation by XRN1. [...] (1093 aa)
     
 
  0.644
PAB1
Hypothetical protein; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through trans [...] (579 aa)
       
  0.592
XP_447635.1
Hypothetical protein (602 aa)
       
  0.592
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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