STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIL1Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity). (339 aa)    
Predicted Functional Partners:
TEF3
Elongation factor 3; The main role of EF-3 may be to transduce nucleoside triphosphate energy into mechanical energy for translocation during translation. EF-3 stimulates EF-1-alpha-dependent binding of aminoacyl- tRNA to the ribosome (By similarity); Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
   
 
 0.990
Q6FW19_CANGA
Uncharacterized protein.
   
 
 0.990
LHS1
Heat shock protein 70 homolog LHS1; Chaperone required for protein translocation and folding in the endoplasmic reticulum.
   
 0.971
KAR2
Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family.
   
 
 0.963
Q6FJY0_CANGA
Ribosomal_L18_c domain-containing protein.
  
 0.896
Q6FJT0_CANGA
Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.
  
 0.895
Q6FTN6_CANGA
KOW domain-containing protein.
  
 0.879
Q6FNU0_CANGA
Uncharacterized protein.
  
 0.875
Q6FPB1_CANGA
Mrpl_C domain-containing protein; Belongs to the bacterial ribosomal protein bL17 family.
  
 0.871
Q6FSL8_CANGA
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 0.868
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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