STRINGSTRING
SFH1 protein (Candida glabrata) - STRING interaction network
"SFH1" - Hypothetical protein in Candida glabrata
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFH1Hypothetical protein; Part of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dep [...] (403 aa)    
Predicted Functional Partners:
XP_449810.1
Hypothetical protein (573 aa)
     
  0.969
ARP4
Hypothetical protein; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes an [...] (493 aa)
     
  0.963
XP_449835.1
Hypothetical protein (984 aa)
     
  0.956
XP_447819.1
Hypothetical protein (547 aa)
     
  0.956
XP_447479.1
Hypothetical protein (507 aa)
     
  0.956
XP_448457.1
Hypothetical protein (529 aa)
     
  0.954
XP_445309.1
Hypothetical protein (482 aa)
     
  0.952
XP_448865.1
Hypothetical protein (556 aa)
     
  0.947
XP_446743.1
Hypothetical protein (1354 aa)
     
  0.937
XP_447768.1
Hypothetical protein (442 aa)
     
 
  0.912
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
Server load: low (9%) [HD]