node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERG11 | ERG2 | P50859 | Q6FKL1 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Uncharacterized protein. | 0.996 |
ERG11 | ERG27 | P50859 | Q6FIV3 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | 3-keto-steroid reductase; Responsible for the reduction of the keto group on the C-3 of sterols. | 0.998 |
ERG11 | ERG3 | P50859 | P50860 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Delta(7)-sterol 5(6)-desaturase; Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. May contribute to the regulation of ergosterol biosynthesis. | 0.982 |
ERG11 | ERG4 | P50859 | Q6FXU8 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Uncharacterized protein. | 0.997 |
ERG11 | ERG5 | P50859 | Q6FJB3 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.736 |
ERG11 | ERG6 | P50859 | Q6FRZ7 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. | 0.998 |
ERG11 | ERG9 | P50859 | Q9HGZ6 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Squalene synthase; Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol; Belongs to the phytoene/squalene synthase family. | 0.998 |
ERG11 | Q6FMX4_CANGA | P50859 | Q6FMX4 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | 0.999 |
ERG11 | Q6FNL2_CANGA | P50859 | Q6FNL2 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.999 |
ERG11 | Q6FQW4_CANGA | P50859 | Q6FQW4 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Uncharacterized protein. | 0.999 |
ERG2 | ERG11 | Q6FKL1 | P50859 | Uncharacterized protein. | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | 0.996 |
ERG2 | ERG27 | Q6FKL1 | Q6FIV3 | Uncharacterized protein. | 3-keto-steroid reductase; Responsible for the reduction of the keto group on the C-3 of sterols. | 0.732 |
ERG2 | ERG3 | Q6FKL1 | P50860 | Uncharacterized protein. | Delta(7)-sterol 5(6)-desaturase; Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. May contribute to the regulation of ergosterol biosynthesis. | 0.997 |
ERG2 | ERG4 | Q6FKL1 | Q6FXU8 | Uncharacterized protein. | Uncharacterized protein. | 0.961 |
ERG2 | ERG5 | Q6FKL1 | Q6FJB3 | Uncharacterized protein. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.937 |
ERG2 | ERG6 | Q6FKL1 | Q6FRZ7 | Uncharacterized protein. | Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. | 0.999 |
ERG2 | ERG9 | Q6FKL1 | Q9HGZ6 | Uncharacterized protein. | Squalene synthase; Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol; Belongs to the phytoene/squalene synthase family. | 0.701 |
ERG2 | Q6FMX4_CANGA | Q6FKL1 | Q6FMX4 | Uncharacterized protein. | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | 0.989 |
ERG2 | Q6FNL2_CANGA | Q6FKL1 | Q6FNL2 | Uncharacterized protein. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.648 |
ERG2 | Q6FQW4_CANGA | Q6FKL1 | Q6FQW4 | Uncharacterized protein. | Uncharacterized protein. | 0.989 |