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PNG1 protein (Candida glabrata) - STRING interaction network
"PNG1" - Hypothetical protein in Candida glabrata
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
PNG1Hypothetical protein; Specifically deglycosylates the denatured form of N- linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl- glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high- mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite [...] (348 aa)    
Predicted Functional Partners:
XP_448830.1
Hypothetical protein (392 aa)
       
  0.976
XP_445784.1
Hypothetical protein (202 aa)
       
  0.960
XP_446470.2
ubiquitin-60S ribosomal protein L40 fusion protein (128 aa)
       
  0.852
XP_445631.1
Hypothetical protein (533 aa)
     
  0.834
XP_446718.1
ubiquitin-40S ribosomal protein S31 fusion protein (152 aa)
       
  0.784
CDC48
Hypothetical protein (830 aa)
     
  0.718
XP_449474.1
Hypothetical protein (373 aa)
       
  0.704
XP_002999515.1
Hypothetical protein (77 aa)
       
  0.704
XP_447462.1
Hypothetical protein (433 aa)
     
  0.694
XP_449580.1
Hypothetical protein; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins (212 aa)
       
  0.673
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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