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CCR4 protein (Candida glabrata) - STRING interaction network
"CCR4" - Hypothetical protein in Candida glabrata
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
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Cooccurence
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[Homology]
Score
CCR4Hypothetical protein; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3’-5’ RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity) (873 aa)    
Predicted Functional Partners:
XP_445707.1
Hypothetical protein (2090 aa)
     
  0.991
XP_445324.1
Hypothetical protein (478 aa)
     
  0.991
XP_449500.1
Hypothetical protein (364 aa)
     
  0.977
XP_447395.1
Hypothetical protein (191 aa)
     
  0.975
XP_445473.1
Hypothetical protein (548 aa)
     
  0.975
XP_447839.1
Hypothetical protein (620 aa)
     
  0.973
XP_447213.1
Hypothetical protein (1135 aa)
     
  0.932
PAB1
Hypothetical protein; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through trans [...] (579 aa)
       
  0.873
XP_447635.1
Hypothetical protein (602 aa)
       
  0.872
XP_447693.1
Hypothetical protein (1163 aa)
       
 
  0.867
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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