node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRE1 | Q6FJ05_CANGA | Q6FWF3 | Q6FJ05 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | HECT domain-containing protein. | 0.684 |
BRE1 | Q6FRD9_CANGA | Q6FWF3 | Q6FRD9 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.438 |
BRE1 | Q6FSS6_CANGA | Q6FWF3 | Q6FSS6 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | Ubiquitin-like domain-containing protein. | 0.643 |
BRE1 | Q6FVW3_CANGA | Q6FWF3 | Q6FVW3 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | Uncharacterized protein. | 0.598 |
BRE1 | RAD18 | Q6FWF3 | Q6FPI4 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | Postreplication repair E3 ubiquitin-protein ligase RAD18; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA. | 0.411 |
BRE1 | UBC2 | Q6FWF3 | Q6FR76 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. | 0.998 |
Q6FJ05_CANGA | BRE1 | Q6FJ05 | Q6FWF3 | HECT domain-containing protein. | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. | 0.684 |
Q6FJ05_CANGA | Q6FNF6_CANGA | Q6FJ05 | Q6FNF6 | HECT domain-containing protein. | UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. | 0.990 |
Q6FJ05_CANGA | Q6FRD9_CANGA | Q6FJ05 | Q6FRD9 | HECT domain-containing protein. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.972 |
Q6FJ05_CANGA | Q6FSS6_CANGA | Q6FJ05 | Q6FSS6 | HECT domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.892 |
Q6FJ05_CANGA | Q6FVW3_CANGA | Q6FJ05 | Q6FVW3 | HECT domain-containing protein. | Uncharacterized protein. | 0.994 |
Q6FJ05_CANGA | RAD18 | Q6FJ05 | Q6FPI4 | HECT domain-containing protein. | Postreplication repair E3 ubiquitin-protein ligase RAD18; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA. | 0.473 |
Q6FJ05_CANGA | UBC2 | Q6FJ05 | Q6FR76 | HECT domain-containing protein. | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. | 0.931 |
Q6FMR9_CANGA | Q6FNF6_CANGA | Q6FMR9 | Q6FNF6 | Ubiquitin-like domain-containing protein. | UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. | 0.837 |
Q6FMR9_CANGA | Q6FPU8_CANGA | Q6FMR9 | Q6FPU8 | Ubiquitin-like domain-containing protein. | Nsp1_C domain-containing protein. | 0.988 |
Q6FMR9_CANGA | Q6FS64_CANGA | Q6FMR9 | Q6FS64 | Ubiquitin-like domain-containing protein. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.771 |
Q6FMR9_CANGA | Q6FSS6_CANGA | Q6FMR9 | Q6FSS6 | Ubiquitin-like domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.783 |
Q6FMR9_CANGA | Q6FVW3_CANGA | Q6FMR9 | Q6FVW3 | Ubiquitin-like domain-containing protein. | Uncharacterized protein. | 0.791 |
Q6FMR9_CANGA | UBC2 | Q6FMR9 | Q6FR76 | Ubiquitin-like domain-containing protein. | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. | 0.902 |
Q6FNF6_CANGA | Q6FJ05_CANGA | Q6FNF6 | Q6FJ05 | UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. | HECT domain-containing protein. | 0.990 |