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HRD3 protein (Candida glabrata) - STRING interaction network
"HRD3" - Hypothetical protein in Candida glabrata
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HRD3Hypothetical protein; Component of the endoplasmic reticulum quality control (ERQC) system involved in ubiquitin-dependent degradation of missfolded endoplasmic reticulum proteins. Component of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD- M). ERAD-L substrates are ubiquitinated through HRD1 in conjunction with the E2 ubiquitin-conjugating enzymes UBC1 and UBC7-CUE [...] (833 aa)    
Predicted Functional Partners:
YOS9
Hypothetical protein; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity) (696 aa)
     
  0.985
XP_445789.1
Hypothetical protein (545 aa)
     
  0.978
CDC48
Hypothetical protein (830 aa)
     
  0.948
XP_449580.1
Hypothetical protein; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins (212 aa)
     
  0.939
XP_446093.1
Hypothetical protein; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins (343 aa)
     
  0.932
XP_446678.1
Hypothetical protein (942 aa)
       
 
  0.904
XP_447003.1
Hypothetical protein (672 aa)
       
 
  0.897
XP_445751.1
Hypothetical protein (717 aa)
     
  0.865
XP_449260.1
Hypothetical protein (352 aa)
       
 
  0.813
CUE1
Hypothetical protein; Component of the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Recruits the soluble ubiquitin-conjugating enzyme UBC7 to the cytoplasmic face of the endoplasmic reticulum membrane where it functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Targets the E2 conjugating enzyme UBC7 to the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic [...] (203 aa)
       
  0.765
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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