STRINGSTRING
XP_449214.1 protein (Candida glabrata) - STRING interaction network
"XP_449214.1" - Hypothetical protein in Candida glabrata
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XP_449214.1Hypothetical protein (845 aa)    
Predicted Functional Partners:
XP_447125.1
Hypothetical protein (298 aa)
     
 
  0.952
CIN8
Hypothetical protein; Required for assembly of the mitotic spindle. Interact with spindle microtubules to produce an outwardly directed force acting upon the poles. Following spindle assembly, CIN8 and KIP1 apparently act to oppose a force that draws separated poles back together. This force seems to be mediated by KAR3 (By similarity) (988 aa)
     
  0.925
TOP2
Hypothetical protein; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (By similarity) (1406 aa)
     
   
  0.897
KAR3
Hypothetical protein (692 aa)
     
  0.849
XP_449441.1
Hypothetical protein (672 aa)
     
  0.818
IPL1
Hypothetical protein; Required for high-fidelity chromosome segregation during the later part of each cell cycle. Acts in opposition to the phosphatase PP1. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension. Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis (By similarity) (358 aa)
     
 
  0.813
XP_447555.1
Hypothetical protein (705 aa)
     
  0.808
XP_446158.1
Hypothetical protein (1483 aa)
     
 
  0.792
XP_445613.1
Hypothetical protein (476 aa)
     
 
  0.790
NDC80
Hypothetical protein; Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (706 aa)
     
   
  0.778
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: C. glabrata, C. glabrata CBS 138, Candida glabrata, Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, Nakaseomyces, Torulopsis glabrata, m. Nakaseomyces, mitosporic Nakaseomyces
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