STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOG1Mitogen-activated protein kinase HOG1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (447 aa)    
Predicted Functional Partners:
SKO1
BZIP domain-containing protein.
    
 0.997
SKN7
Response regulatory domain-containing protein.
   
 0.995
Q6FL74_CANGA
Protein kinase domain-containing protein.
  
0.987
Q6FWM3_CANGA
PPM-type phosphatase domain-containing protein.
   
 0.981
Q6FPJ8_CANGA
Uncharacterized protein.
   
 0.980
HOT1
High-osmolarity-induced transcription protein 1; Required for a complete transcriptional response to osmotic stress; Belongs to the HOT1 family.
    
 0.978
Q6FLK0_CANGA
Uncharacterized protein.
    
 0.975
MSN2
Uncharacterized protein.
   
 0.969
MSN4
Uncharacterized protein.
    
 0.967
SHO1
High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
   
 
 0.931
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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