STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPAC27E2.03cObg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). Negatively regulates the G2/M transition in the cell cycle; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. (392 aa)    
Predicted Functional Partners:
tma20
Translation machinery-associated protein 20; Involved in translation.
 
 
    0.905
nif1
Mitosis inhibitor nif1; Functions as a negative regulator of mitosis. It interacts with the C-terminal of nim1, thereby inhibiting its kinase activity which phosphorylates wee1.
  
  
 0.757
pth1
Probable peptidyl-tRNA hydrolase; Belongs to the PTH family.
  
  
 0.653
nud3
Nuclear movement protein nudc; Required for nuclear movement. May interact between microtubules and nuclei and/or may be involved in the generation of force used to move nuclei during interphase (By similarity). Belongs to the nudC family.
   
  
 0.647
mrs1
Probable arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
  
  
 0.614
gly1
Probable low-specificity L-threonine aldolase.
 
    0.606
cts1
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
   
 
 0.592
SPAC29A4.02c
Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
   
 
 0.584
mrf1
Putative peptide chain release factor 1, mitochondrial; Belongs to the prokaryotic/mitochondrial release factor family.
  
  
 0.578
frs1
Phenylalanine--tRNA ligase beta subunit.
  
  
 0.560
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.