STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPBC19C7.11Putative anion/proton exchange transporter C19C7.11; Anion/proton exchange transporter involved in iron and copper cation homeostasis. (766 aa)    
Predicted Functional Partners:
SPBC887.02
Uncharacterized chloride channel protein C887.02; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family.
  
 
 
0.834
msh1
MutS protein homolog 1; Involved in mitochondrial DNA repair; Belongs to the DNA mismatch repair MutS family.
      
 0.760
prp1
Pre-mRNA-splicing factor prp1; Involved in pre-mRNA splicing. Interacts with prp6 and prp13. May also be involved in the regulation of the G0-G1/G2 transition. Required for pre-spliceosome formation, which is the first step of pre- mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site- 3' splice 3'-exon region.
   
  
 0.751
abo1
Uncharacterized AAA domain-containing protein C31G5.19.
   
  
 0.640
spt16
FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
      
 0.630
hrp1
Chromodomain helicase hrp1; Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity.
   
 
 0.587
SPBC12C2.04
Uncharacterized protein C12C2.04; To S.pombe SpAC2E11.17.
     
 0.585
rct1
Peptidyl-prolyl cis-trans isomerase cyp6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
 
 
    0.507
SPAC29A4.02c
Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
     
 0.447
ura6
Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
   
 
  0.429
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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