node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cxr1 | lea1 | O60176 | Q9USX8 | Uncharacterized RNA-binding protein C23E6.01c. | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | 0.903 |
cxr1 | luc7 | O60176 | Q9USM4 | Uncharacterized RNA-binding protein C23E6.01c. | U1 snRNP-associated protein usp106; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway. | 0.902 |
cxr1 | prp10 | O60176 | Q10178 | Uncharacterized RNA-binding protein C23E6.01c. | U2 snRNP component prp10; Contacts pre-mRNA on both sides of the branch site early in spliceosome assembly; Belongs to the SF3B1 family. | 0.897 |
cxr1 | prp2 | O60176 | P36629 | Uncharacterized RNA-binding protein C23E6.01c. | Splicing factor U2AF 59 kDa subunit; Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC- 3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns; Belongs to the splicing factor SR family. | 0.897 |
cxr1 | smd1 | O60176 | O42661 | Uncharacterized RNA-binding protein C23E6.01c. | Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity). | 0.897 |
cxr1 | sme1 | O60176 | Q9USZ3 | Uncharacterized RNA-binding protein C23E6.01c. | Small nuclear ribonucleoprotein E; Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification (By similarity). | 0.897 |
cxr1 | usp101 | O60176 | O13829 | Uncharacterized RNA-binding protein C23E6.01c. | U1 small nuclear ribonucleoprotein 70 kDa homolog; Involved in nuclear mRNA splicing (By similarity). Essential for growth. | 0.902 |
cxr1 | usp103 | O60176 | Q9P794 | Uncharacterized RNA-binding protein C23E6.01c. | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. usp103/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. | 0.907 |
cxr1 | usp105 | O60176 | O74970 | Uncharacterized RNA-binding protein C23E6.01c. | Pre-mRNA-processing factor 39; Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction. Has a direct role in the assembly or function of a catalytically active spliceosome (By similarity); Belongs to the PRP39 family. | 0.936 |
cxr1 | usp107 | O60176 | Q8WZK0 | Uncharacterized RNA-binding protein C23E6.01c. | U1 snRNP-associated protein usp107; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway. | 0.904 |
lea1 | cxr1 | Q9USX8 | O60176 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | Uncharacterized RNA-binding protein C23E6.01c. | 0.903 |
lea1 | luc7 | Q9USX8 | Q9USM4 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | U1 snRNP-associated protein usp106; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway. | 0.996 |
lea1 | prp10 | Q9USX8 | Q10178 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | U2 snRNP component prp10; Contacts pre-mRNA on both sides of the branch site early in spliceosome assembly; Belongs to the SF3B1 family. | 0.999 |
lea1 | prp2 | Q9USX8 | P36629 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | Splicing factor U2AF 59 kDa subunit; Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC- 3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns; Belongs to the splicing factor SR family. | 0.995 |
lea1 | smd1 | Q9USX8 | O42661 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity). | 0.999 |
lea1 | sme1 | Q9USX8 | Q9USZ3 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | Small nuclear ribonucleoprotein E; Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification (By similarity). | 0.999 |
lea1 | usp101 | Q9USX8 | O13829 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | U1 small nuclear ribonucleoprotein 70 kDa homolog; Involved in nuclear mRNA splicing (By similarity). Essential for growth. | 0.998 |
lea1 | usp103 | Q9USX8 | Q9P794 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. usp103/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. | 0.998 |
lea1 | usp105 | Q9USX8 | O74970 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | Pre-mRNA-processing factor 39; Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction. Has a direct role in the assembly or function of a catalytically active spliceosome (By similarity); Belongs to the PRP39 family. | 0.999 |
lea1 | usp107 | Q9USX8 | Q8WZK0 | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity). | U1 snRNP-associated protein usp107; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway. | 0.998 |