STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPBC428.10Uncharacterized protein C428.10. (845 aa)    
Predicted Functional Partners:
mug8
Meiotically up-regulated gene 8 protein; Has a role in meiosis and septation.
    
 
 0.775
SPAPB1A11.02
AB hydrolase superfamily protein B1A11.02; Belongs to the AB hydrolase superfamily.
   
  
 0.764
mbx2
MADS-box transcription factor pvg4; Acts in transcription regulation. May bind to a MEF2-like typee II promoter sequence.
   
 
 0.586
swd22
Uncharacterized WD repeat-containing protein C824.04.
      
 0.530
ddr48
Uncharacterized protein C23H3.15c.
   
   0.468
eis1
Uncharacterized protein C63.14.
   
   0.457
SPBC215.11c
Uncharacterized oxidoreductase C215.11c.
   
   0.447
tcb2
Meiotically up-regulated gene 190 protein; Has a role in meiosis.
   
   0.446
gst3
Glutathione S-transferase 3; May have a role in the detoxification of various heavy metals.
   
   0.427
etr1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Required for respiration and the maintenance of the mitochondrial compartment. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
   
   0.418
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.