STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sea4Uncharacterized WD repeat-containing protein C12G12.01c; Belongs to the WD repeat mio family. (905 aa)    
Predicted Functional Partners:
sea3
Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05; May be involved in telomere capping.
   
 0.999
sea2
Uncharacterized WD repeat-containing protein C4F8.11.
   
 0.999
iml1
Vacuolar membrane-associated protein iml1.
   
 0.999
sec13
Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...]
    
 0.999
seh1
Nucleoporin seh1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
    
 0.999
npr2
Nitrogen permease regulator 2 homolog; Mediates inactivation of the TORC1 complex in response to amino acid starvation. Post-transcriptional regulator of nitrogen permeases (By similarity); Belongs to the NPR2 family.
    
 0.998
npr3
Nitrogen permease regulator 3-like protein; Belongs to the NPR3 family.
    
 0.995
gtr1
GTP-binding protein gtr1; GTPase. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome (By similarity).
   
 
 0.961
gtr2
GTP-binding protein gtr2; GTPase. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome (By similarity).
  
 
 
 0.929
lam1
Uncharacterized protein C29A10.17.
      
 0.742
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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