STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mak16Protein mak16. (302 aa)    
Predicted Functional Partners:
SPAC4F8.04
Brix domain-containing protein C4F8.04.
   
 0.999
wdr74
Ribosome biogenesis protein nsa1; Involved in the biogenesis of the 60S ribosomal subunit.
   
 0.998
rlp24
Ribosome biogenesis protein rlp24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of nog1 to pre-60S particles. Activates and recruits ATPase afg2 to cytoplasmic pre-60S ribosomal particles.
   
  0.998
nop52
Ribosomal RNA-processing protein 1 homolog; Required for 27S rRNA processing to 25S and 5.8S. Belongs to the RRP1 family.
   
 0.998
ebp2
Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA.
   
 0.997
noc3
Nucleolar complex-associated protein 3; May be required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.
   
 0.997
ytm1
Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 0.996
spb1
AdoMet-dependent rRNA methyltransferase spb1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
   
  0.995
SPCC1827.05c
Uncharacterized RNA-binding protein C1827.05c.
   
 
 0.995
brx1
Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
   0.994
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.