node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHFR-1 | DUT1 | O62583 | Q8SRS0 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.634 |
DHFR-1 | Q8SS02_ENCCU | O62583 | Q8SS02 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | DEOXYURIDINE 5'TRIPHOSPHATE NUCLEOTIDOHYDROLASE. | 0.634 |
DHFR-1 | Q8SS22_ENCCU | O62583 | Q8SS22 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | THYMIDYLATE KINASE. | 0.963 |
DHFR-1 | RIR1_ENCCU | O62583 | Q8SR37 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.460 |
DHFR-1 | SHMT-1 | O62583 | O62585 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.995 |
DHFR-1 | TK | O62583 | O96720 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Thymidine kinase. | 0.946 |
DHFR-1 | TS-1 | O62583 | O62584 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Thymidylate synthase 1/2; Belongs to the thymidylate synthase family. | 0.997 |
DHFR-1 | TS-3 | O62583 | Q8SRG2 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | Thymidylate synthase 3; Belongs to the thymidylate synthase family. | 0.997 |
DUT1 | DHFR-1 | Q8SRS0 | O62583 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | 0.634 |
DUT1 | Q8SS22_ENCCU | Q8SRS0 | Q8SS22 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | THYMIDYLATE KINASE. | 0.958 |
DUT1 | RIR1_ENCCU | Q8SRS0 | Q8SR37 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.840 |
DUT1 | SHMT-1 | Q8SRS0 | O62585 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.401 |
DUT1 | TK | Q8SRS0 | O96720 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidine kinase. | 0.967 |
DUT1 | TS-1 | Q8SRS0 | O62584 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase 1/2; Belongs to the thymidylate synthase family. | 0.972 |
DUT1 | TS-3 | Q8SRS0 | Q8SRG2 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase 3; Belongs to the thymidylate synthase family. | 0.972 |
Q8SQJ5_ENCCU | Q8SS22_ENCCU | Q8SQJ5 | Q8SS22 | BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASE FAMILY. | THYMIDYLATE KINASE. | 0.750 |
Q8SQJ5_ENCCU | TK | Q8SQJ5 | O96720 | BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASE FAMILY. | Thymidine kinase. | 0.771 |
Q8SQJ5_ENCCU | TS-1 | Q8SQJ5 | O62584 | BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASE FAMILY. | Thymidylate synthase 1/2; Belongs to the thymidylate synthase family. | 0.700 |
Q8SQJ5_ENCCU | TS-3 | Q8SQJ5 | Q8SRG2 | BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASE FAMILY. | Thymidylate synthase 3; Belongs to the thymidylate synthase family. | 0.700 |
Q8SS02_ENCCU | DHFR-1 | Q8SS02 | O62583 | DEOXYURIDINE 5'TRIPHOSPHATE NUCLEOTIDOHYDROLASE. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | 0.634 |