STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALDR_ENCCUAldose reductase; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. (301 aa)    
Predicted Functional Partners:
DHFR-1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
  
 
 0.925
Q8SU17_ENCCU
Phosphotransferase.
   
 
 0.852
Q8SU08_ENCCU
Uncharacterized protein.
  
  
 0.780
Q8SVF0_ENCCU
TRANSKETOLASE.
   
 
 0.679
Q8SRX1_ENCCU
6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family.
  
 
 0.658
Q8SUA4_ENCCU
ENOLASE.
   
 
 0.651
Q8STL9_ENCCU
Putative oxidoreductase.
     
 0.596
Q8SQZ1_ENCCU
Triosephosphate isomerase.
  
 
 0.594
Q8SRJ8_ENCCU
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.587
GPX_ENCCU
Probable phospholipid hydroperoxide glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione; Belongs to the glutathione peroxidase family.
  
 
 0.557
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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