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Phatr18280 protein (Phaeodactylum tricornutum) - STRING interaction network
"Phatr18280" - Predicted protein in Phaeodactylum tricornutum
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phatr18280Predicted protein (504 aa)    
Predicted Functional Partners:
Phatr44708
Predicted protein (790 aa)
     
  0.926
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (421 aa)
   
  0.862
Phatr46971
Predicted protein (696 aa)
   
  0.862
Phatr47417
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (1009 aa)
   
  0.862
Phatr1241
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (520 aa)
 
  0.862
Phatr48206
Predicted protein (794 aa)
   
  0.860
Phatr46734
Predicted protein (894 aa)
   
  0.860
RPA1
Replication protein a large 70 kD subunit (606 aa)
     
  0.859
Phatr54612
Ercc4-like protein (736 aa)
     
  0.855
Phatr45914
Predicted protein (746 aa)
     
 
  0.846
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 2850
Other names: Bacillariophyceae, Bacillariophycidae, Naviculales, P. tricornutum, Phaeodactylaceae, Phaeodactylum, Phaeodactylum tricornutum, Raphid, pennate diatoms
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