Groups of genes that are frequently observed in each other's genomic neighborhood.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Predicted protein (232 aa)
Predicted Functional Partners:
Ubiquitin-like protein (268 aa)
Predicted proteinUbiquitin extension protein 4 (381 aa)
Predicted protein (205 aa)
COP9 SigNalosome subunit 5 (370 aa)
Ubiquitin extension protein 3 (155 aa)
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (490 aa)