Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phatr50061
Predicted protein (886 aa)
Predicted Functional Partners:
Phatr16147
Predicted protein (200 aa)
0.487
RpoT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (576 aa)
0.465
Phatrdraft1384
Predicted protein (343 aa)
0.422
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 2850 Other names: Bacillariophyceae, Bacillariophycidae, Naviculales, P. tricornutum, Phaeodactylaceae, Phaeodactylum, Phaeodactylum tricornutum, Raphid, pennate diatoms
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
Phatr16147
Phatr50061
Phatr16147
Phatr50061
Predicted protein
Predicted protein
0.487
Phatr16147
Phatrdraft1384
Phatr16147
Phatrdraft1384
Predicted protein
Predicted protein
0.682
Phatr50061
Phatr16147
Phatr50061
Phatr16147
Predicted protein
Predicted protein
0.487
Phatr50061
Phatrdraft1384
Phatr50061
Phatrdraft1384
Predicted protein
Predicted protein
0.422
Phatr50061
RpoT
Phatr50061
Phatr15863
Predicted protein
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
0.465
Phatrdraft1384
Phatr16147
Phatrdraft1384
Phatr16147
Predicted protein
Predicted protein
0.682
Phatrdraft1384
Phatr50061
Phatrdraft1384
Phatr50061
Predicted protein
Predicted protein
0.422
RpoT
Phatr50061
Phatr15863
Phatr50061
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Predicted protein
0.465
Network Stats
Network Stats analysis is still ongoing, please wait ...
Functional enrichments in your networkNote: some enrichments may be expected here (why?)
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: