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Mlh1 protein (Phaeodactylum tricornutum) - STRING interaction network
"Mlh1" - Mutl-like protein 1 in Phaeodactylum tricornutum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlh1Mutl-like protein 1 (695 aa)    
Predicted Functional Partners:
Phatr14607
Predicted protein (337 aa)
   
0.979
Phatr19604
Predicted protein (363 aa)
 
  0.960
MSH5
Muts-like protein 5 (376 aa)
 
  0.952
MSH4
Muts-like protein 4 (116 aa)
 
  0.951
Phatr53969
Predicted protein (1423 aa)
   
  0.913
Phatr53933
Predicted protein (1258 aa)
   
  0.913
Phatr48206
Predicted protein (794 aa)
   
  0.872
Phatr46734
Predicted protein (894 aa)
   
  0.872
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (421 aa)
   
  0.868
Phatr46971
Predicted protein (696 aa)
   
  0.868
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 2850
Other names: Bacillariophyceae, Bacillariophycidae, Naviculales, P. tricornutum, Phaeodactylaceae, Phaeodactylum, Phaeodactylum tricornutum, Raphid, pennate diatoms
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