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AP1alpha protein (Phaeodactylum tricornutum) - STRING interaction network
"AP1alpha" - AP-2 complex subunit alpha in Phaeodactylum tricornutum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP1alphaAP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (1019 aa)    
Predicted Functional Partners:
AP2mu
Predicted protein; Belongs to the adaptor complexes medium subunit family (425 aa)
     
  0.999
AP2sigma
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family (152 aa)
     
  0.998
Phatr42442
Predicted protein (980 aa)
     
 
  0.962
CHC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (1702 aa)
     
 
  0.957
Phatr8741
Predicted protein (92 aa)
     
 
  0.952
Phatrdraft1735
Predicted protein (890 aa)
     
 
  0.932
AP4beta
Predicted protein (805 aa)
     
 
  0.932
COPgamma
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (910 aa)
     
 
  0.773
AP1mu
Predicted protein; Belongs to the adaptor complexes medium subunit family (439 aa)
     
 
  0.731
AP4mu
Predicted protein; Belongs to the adaptor complexes medium subunit family (470 aa)
     
 
  0.731
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 2850
Other names: P. tricornutum, Phaeodactylum tricornutum
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