• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Phatr8810 protein (Phaeodactylum tricornutum) - STRING interaction network
"Phatr8810" - DNA topoisomerase in Phaeodactylum tricornutum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phatr8810DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (868 aa)    
Predicted Functional Partners:
Phatr13384
Predicted protein (594 aa)
     
 
  0.895
Phatr54612
Ercc4-like protein (736 aa)
   
 
  0.869
Phatr47417
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (1009 aa)
   
 
0.851
Phatrdraft913
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP (386 aa)
           
  0.798
Phatr1690
Predicted protein (495 aa)
   
   
  0.724
rpl14
Predicted protein; Belongs to the universal ribosomal protein uL14 family (143 aa)
     
   
  0.677
Phatrdraft1666
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis (558 aa)
           
  0.637
rps19
Predicted protein; Belongs to the universal ribosomal protein uS19 family (147 aa)
     
   
  0.627
Phatr9199
Predicted protein; Belongs to the universal ribosomal protein uS15 family (151 aa)
     
   
  0.625
Phatr35766
Predicted protein (828 aa)
     
   
  0.624
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 2850
Other names: P. tricornutum, Phaeodactylum tricornutum
Server load: low (7%) [HD]