STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nudFNuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (459 aa)    
Predicted Functional Partners:
TSTA_067220
Dynein heavy chain.
    
 0.997
TSTA_091440
Nuclear distribution protein NudE.
    
 
 0.969
TSTA_011810
Dynein intermediate chain, putative.
   
 0.953
TSTA_036440
Nuclear movement protein NudC.
    
 0.949
TSTA_057010
Dynactin, putative.
    
 0.946
TSTA_078810
Uncharacterized protein.
    
 0.941
TSTA_018860
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.941
TSTA_114220
Dynein family protein.
   
 0.856
TSTA_016340
Uncharacterized protein.
    
 0.852
TSTA_058410
Serine/threonine protein kinase, putative.
    
  0.830
Your Current Organism:
Talaromyces stipitatus
NCBI taxonomy Id: 441959
Other names: T. stipitatus ATCC 10500, Talaromyces stipitatus ATCC 10500
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