STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_06323Histidine biosynthesis trifunctional protein. (863 aa)    
Predicted Functional Partners:
PISL3812_05860
Imidazoleglycerol-phosphate dehydratase.
 
 0.999
PISL3812_06266
Histidinol-phosphate aminotransferase.
 
 0.998
PISL3812_08301
ATP phosphoribosyltransferase.
 
 
 0.998
PISL3812_05625
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
 
 0.997
PISL3812_01916
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
 
 0.996
PISL3812_02452
Bifunctional polynucleotide phosphatase/kinase.
  
 
 0.994
PISL3812_05112
Uncharacterized protein.
  
 
 0.994
PISL3812_00016
Tryptophan synthase.
  
  
 0.989
PISL3812_08936
Tryptophan synthase.
  
  
 0.989
PISL3812_08511
Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
  
 
 0.988
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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