STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SeMB42_g07464Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (286 aa)    
Predicted Functional Partners:
SeMB42_g02199
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 0.999
SeMB42_g07202
WD_REPEATS_REGION domain-containing protein.
   
 0.997
SeMB42_g01933
Protein kinase domain-containing protein.
    
 
 0.971
SeMB42_g06143
Lipase_3 domain-containing protein.
   
 
 0.968
SeMB42_g05397
Uncharacterized protein.
    
 0.967
SeMB42_g06665
Autophagy-related protein.
   
 0.937
SeMB42_g05990
Protein kinase domain-containing protein.
    
 
 0.931
SeMB42_g07844
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.915
SeMB42_g05903
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.861
SeMB42_g03103
Uncharacterized protein.
     
 0.843
Your Current Organism:
Synchytrium endobioticum
NCBI taxonomy Id: 286115
Other names: S. endobioticum
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.