STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PirRTwo-component system, ompr family, response regulator pfer; Transcriptional regulatory , C terminal family protein (239 aa)    
Predicted Functional Partners:
PirS
annotation not available
 0.995
gacS
annotation not available
 
 
0.995
DR97_3759
annotation not available
 
 
 0.993
bvgS
annotation not available
 
 
 0.988
pfeS
Two-component system, ompr family, sensor histidine kinase pfes; Member of the two-component regulatory system PfeR/PfeS. May activate PfeR by phosphorylation
 0.972
aruS
Putative two-component sensor; Member of the two-component regulatory system AruS/AruR, which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Probably functions as a sensor kinase that phosphorylates AruR
 
 0.904
FecI
Rna polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily
   
  
 0.892
DR97_4892
annotation not available
 
 0.881
piuC
annotation not available
   
  
 0.873
pfeR
Two-component system, ompr family, response regulator pfer; Member of the two-component regulatory system PfeR/PfeS. Activates expression of the ferric enterobactin receptor
  
 
 
0.866
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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