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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argRArac family transcriptional regulator, l-arginine-responsive activator; ArgR could be a transcriptional activator of the dauBAR operon in response to the presence of L-Arg (329 aa)    
Predicted Functional Partners:
aotM
Octopine transport system permease protein OccM; HEQRo_perm_3TM: amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein
  
  
 0.958
aotQ
Histidine transport system permease protein HisQ; HEQRo_perm_3TM: amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein
     
 0.952
aotP
Arginine/ornithine transport system atp-binding protein; Part of the arginine-inducible binding-protein-dependent transport system for arginine and ornithine. Probably responsible for energy coupling to the transport system
  
  
 0.927
AotO
annotation not available
  
  
 0.919
aruF
Arginine/ornithine succinyltransferase, alpha subunit; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. Also acts on L-ornithine
 
   
 0.884
astA
Arginine/ornithine succinyltransferase aii subunit; arg_catab_AstA: arginine N-succinyltransferase
 
   
 0.881
aruC
Bifunctional n-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Transaminates both N(2)-acetylornithine and N(2)- succinylornithine
     
 0.858
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase (ArgG) involved in the final step in arginine biosynthesis
      
 0.851
arcB
Ornithine carbamoyltransferase; Involved in the catabolism of arginine. Catalyzes the phosphorolysis of citrulline, the reverse reaction of the biosynthetic one, yielding ornithine and carbamoyl phosphate which serve to generate ATP from ADP . This catabolic OTCase does not carry out the biosynthetic reaction because of a poor affinity and a marked cooperativity for carbamoyl phosphate
      
 0.845
aotJ
Arginine/ornithine transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family
     
 0.815
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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