node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FumA | MaeB | DR97_1509 | DR97_2401 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | annotation not available | 0.981 |
FumA | acnA | DR97_1509 | DR97_373 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein | 0.963 |
FumA | fumC | DR97_1509 | DR97_1090 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | 0.995 |
FumA | gltA | DR97_1509 | DR97_309 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Type ii citrate synthase; cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family | 0.972 |
FumA | mqo1 | DR97_1509 | DR97_4469 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Malate dehydrogenase (quinone); Probable malate:quinone oxidoreductase; Mal_quin_oxido: malate dehydrogenase | 0.924 |
FumA | sdhA | DR97_1509 | DR97_306 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.990 |
FumA | sdhB | DR97_1509 | DR97_305 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein | 0.968 |
FumA | sdhC | DR97_1509 | DR97_308 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit | 0.997 |
FumA | sucA | DR97_1509 | DR97_304 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component | 0.907 |
FumA | sucD | DR97_1509 | DR97_300 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP | 0.915 |
MaeB | FumA | DR97_2401 | DR97_1509 | annotation not available | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | 0.981 |
MaeB | fumC | DR97_2401 | DR97_1090 | annotation not available | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | 0.942 |
MaeB | gltA | DR97_2401 | DR97_309 | annotation not available | Type ii citrate synthase; cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family | 0.933 |
MaeB | mqo1 | DR97_2401 | DR97_4469 | annotation not available | Malate dehydrogenase (quinone); Probable malate:quinone oxidoreductase; Mal_quin_oxido: malate dehydrogenase | 0.916 |
MaeB | sucA | DR97_2401 | DR97_304 | annotation not available | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component | 0.580 |
acnA | FumA | DR97_373 | DR97_1509 | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | 0.963 |
acnA | fumC | DR97_373 | DR97_1090 | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate | 0.942 |
acnA | gltA | DR97_373 | DR97_309 | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein | Type ii citrate synthase; cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family | 0.995 |
acnA | sdhA | DR97_373 | DR97_306 | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.858 |
acnA | sdhB | DR97_373 | DR97_305 | Aconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein | 0.648 |