STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
trxB2TRX_reduct: thioredoxin-disulfide reductase; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family (316 aa)    
Predicted Functional Partners:
trxA
Thioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions
 
 
 0.975
ahpC
Alkyl hydroperoxide reductase subunit c; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
 
 
 0.961
gor
Pyridine nucleotide-disulfide oxidoreductase family protein; Maintains high levels of reduced glutathione in the cytosol
  
 
 0.944
Trx-1
Putative thioredoxin; Thioredoxin: thioredoxin
 
 
 0.940
DR97_1096
Alkyl hydroperoxide reductase; C-terminal domain of 1-Cys peroxiredoxin family protein
  
 
 0.927
AhpC
Hypothetical protein; Alkyl hydroperoxide reductase; C-terminal domain of 1-Cys peroxiredoxin family protein
  
 
 0.891
bcp
annotation not available
 
  
 0.879
katB
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
   
 
 0.875
DR97_1334
Thioredoxin: thioredoxin
 
 
 0.863
rpe
Belongs to the ribulose-phosphate 3-epimerase family
  
 
 0.857
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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