STRINGSTRING
menG protein (Pseudomonas aeruginosa) - STRING interaction network
"menG" - 4-hydroxy-4-methyl-2-oxoglutarate aldolase in Pseudomonas aeruginosa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menG4-hydroxy-4-methyl-2-oxoglutarate aldolase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (162 aa)    
Predicted Functional Partners:
estX
annotation not available (336 aa)
         
  0.712
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (791 aa)
              0.709
cmaX
annotation not available (332 aa)
         
  0.653
deaD
ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation (556 aa)
       
 
  0.620
srmB
ATP-dependent RNA helicase; Helicase conserved C-terminal domain protein; Belongs to the DEAD box helicase family (441 aa)
       
 
  0.620
rhlB
ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA; Belongs to the DEAD box helicase family. RhlB subfamily (507 aa)
       
 
  0.620
DR97_3916
ATP-dependent RNA helicase rhlE; Helicase conserved C-terminal domain protein; Belongs to the DEAD box helicase family (449 aa)
       
 
  0.620
DR97_3396
ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA (639 aa)
       
 
  0.620
dbpA
ATP-independent RNA helicase dbpA; Helicase conserved C-terminal domain protein; Belongs to the DEAD box helicase family (458 aa)
       
 
  0.534
DR97_1986
annotation not available (1757 aa)
     
 
  0.523
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
Server load: low (8%) [HD]