STRINGSTRING
prpD protein (Pseudomonas aeruginosa) - STRING interaction network
prpD: 2-methylcitrate dehydratase in Pseudomonas aeruginosa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpDprpD- 2-methylcitrate dehydratase (494 aa)    
Predicted Functional Partners:
prpC
cit_synth_II- 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family (375 aa)
  0.999
prpF
prpF- putative AcnD-accessory protein PrpF (395 aa)
   
 
  0.995
acnD
Aconitate hydratase; 2met_isocit_dHY- 2-methylisocitrate dehydratase, Fe/S-dependent (868 aa)
   
 
  0.991
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family (298 aa)
 
   
  0.984
acnB
acnB- aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family (869 aa)
         
  0.954
bcpA
Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily (276 aa)
 
   
  0.791
gltA
cit_synth_I- citrate (Si)-synthase; Belongs to the citrate synthase family (428 aa)
 
 
  0.701
prpE
annotation not available (628 aa)
   
   
  0.691
DR97_4195
annotation not available (274 aa)
 
   
  0.524
phnW
2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily (371 aa)
   
        0.489
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
Server load: low (10%) [HD]