node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1448 | DR97_1449 | DR97_1448 | DR97_1449 | Hypothetical protein; Uncharacterized protein | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | 0.988 |
DR97_1448 | dnaE2 | DR97_1448 | DR97_1450 | Hypothetical protein; Uncharacterized protein | Dna polymerase iii, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase | 0.985 |
DR97_1448 | lexA | DR97_1448 | DR97_4930 | Hypothetical protein; Uncharacterized protein | Repressor lexa; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | 0.632 |
DR97_1449 | DR97_1448 | DR97_1449 | DR97_1448 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | Hypothetical protein; Uncharacterized protein | 0.988 |
DR97_1449 | DR97_4703 | DR97_1449 | DR97_4703 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | annotation not available | 0.682 |
DR97_1449 | dnaE2 | DR97_1449 | DR97_1450 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | Dna polymerase iii, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase | 0.998 |
DR97_1449 | dnaN | DR97_1449 | DR97_2951 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | 0.887 |
DR97_1449 | dnaX | DR97_1449 | DR97_404 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | Dna polymerase iii, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity | 0.681 |
DR97_1449 | holA | DR97_1449 | DR97_3876 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | holA: DNA polymerase III, delta subunit | 0.841 |
DR97_1449 | lexA | DR97_1449 | DR97_4930 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | Repressor lexa; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | 0.944 |
DR97_1449 | polA | DR97_1449 | DR97_2871 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.907 |
DR97_1449 | recA | DR97_1449 | DR97_4322 | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | Recombination protein reca; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage | 0.829 |
DR97_4703 | DR97_1449 | DR97_4703 | DR97_1449 | annotation not available | Hypothetical protein; impB/mucB/samB family C-terminal domain protein | 0.682 |
DR97_4703 | dinB | DR97_4703 | DR97_1016 | annotation not available | Hypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII | 0.698 |
DR97_4703 | dnaE2 | DR97_4703 | DR97_1450 | annotation not available | Dna polymerase iii, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase | 0.937 |
DR97_4703 | dnaN | DR97_4703 | DR97_2951 | annotation not available | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | 0.967 |
DR97_4703 | dnaX | DR97_4703 | DR97_404 | annotation not available | Dna polymerase iii, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity | 0.963 |
DR97_4703 | holA | DR97_4703 | DR97_3876 | annotation not available | holA: DNA polymerase III, delta subunit | 0.961 |
DR97_4703 | lexA | DR97_4703 | DR97_4930 | annotation not available | Repressor lexa; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | 0.738 |
DR97_4703 | polA | DR97_4703 | DR97_2871 | annotation not available | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.815 |