| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR97_1508 | DR97_2126 | DR97_1508 | DR97_2126 | GGDEF: diguanylate cyclase domain protein | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | 0.748 |
| DR97_1508 | DR97_3759 | DR97_1508 | DR97_3759 | GGDEF: diguanylate cyclase domain protein | annotation not available | 0.898 |
| DR97_1508 | bifA | DR97_1508 | DR97_1545 | GGDEF: diguanylate cyclase domain protein | Ggdef domain/eal domain-containing protein; Protein BifA; GGDEF: diguanylate cyclase domain protein | 0.772 |
| DR97_1508 | gacS | DR97_1508 | DR97_1011 | GGDEF: diguanylate cyclase domain protein | annotation not available | 0.687 |
| DR97_1508 | retS | DR97_1508 | DR97_2207 | GGDEF: diguanylate cyclase domain protein | annotation not available | 0.505 |
| DR97_2126 | DR97_1508 | DR97_2126 | DR97_1508 | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | GGDEF: diguanylate cyclase domain protein | 0.748 |
| DR97_2126 | DR97_3125 | DR97_2126 | DR97_3125 | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | 0.862 |
| DR97_2126 | DR97_3759 | DR97_2126 | DR97_3759 | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | annotation not available | 0.829 |
| DR97_2126 | bifA | DR97_2126 | DR97_1545 | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | Ggdef domain/eal domain-containing protein; Protein BifA; GGDEF: diguanylate cyclase domain protein | 0.797 |
| DR97_2126 | gacS | DR97_2126 | DR97_1011 | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | annotation not available | 0.722 |
| DR97_2126 | retS | DR97_2126 | DR97_2207 | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | annotation not available | 0.601 |
| DR97_3125 | DR97_2126 | DR97_3125 | DR97_2126 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | 0.862 |
| DR97_3125 | DR97_3759 | DR97_3125 | DR97_3759 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | annotation not available | 0.909 |
| DR97_3125 | DR97_4949 | DR97_3125 | DR97_4949 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | Hypothetical protein; Phosphodiesterase | 0.854 |
| DR97_3125 | bifA | DR97_3125 | DR97_1545 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | Ggdef domain/eal domain-containing protein; Protein BifA; GGDEF: diguanylate cyclase domain protein | 0.638 |
| DR97_3125 | fleQ | DR97_3125 | DR97_840 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | Sigma-54 dependent transcriptional regulator, flagellar regulatory protein; AAA+ ATPase enhancer-binding protein that acts as a transcription regulator and plays a role in the modulation of mucin adhesion and flagellar gene expression In addition to flagella genes, regulates also expression of biofilm-related genes . Functions as a transcriptional repressor in the absence of c-di-GMP and as an activator when c-di-GMP is present | 0.685 |
| DR97_3125 | gacS | DR97_3125 | DR97_1011 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | annotation not available | 0.838 |
| DR97_3125 | retS | DR97_3125 | DR97_2207 | Response regulator PleD; GGDEF: diguanylate cyclase domain protein | annotation not available | 0.683 |
| DR97_3759 | DR97_1508 | DR97_3759 | DR97_1508 | annotation not available | GGDEF: diguanylate cyclase domain protein | 0.898 |
| DR97_3759 | DR97_2126 | DR97_3759 | DR97_2126 | annotation not available | Putative two-component system response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture . May act preferentially as a pGpG binding protein | 0.829 |
STRING Database User Survey
