pncB2 protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pncB2

Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (398 aa)

Predicted Functional Partners:

pncA

0.985

nadD

0.944

nadC

0.936

cinA

0.916

nudC

0.909

mazG

0.903

surE

0.902

DR97_2545

0.900

DR97_287

0.900

DR97_1980

0.837

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_1980	pncB2	DR97_1980	DR97_1553	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	0.837
DR97_2545	cinA	DR97_2545	DR97_4321	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	0.902
DR97_2545	mazG	DR97_2545	DR97_1004	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	0.903
DR97_2545	nadC	DR97_2545	DR97_1703	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family	0.902
DR97_2545	nadD	DR97_2545	DR97_3861	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	annotation not available	0.905
DR97_2545	nudC	DR97_2545	DR97_55	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	annotation not available	0.900
DR97_2545	pncB2	DR97_2545	DR97_1553	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	0.900
DR97_2545	surE	DR97_2545	DR97_4314	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.804
DR97_287	pncA	DR97_287	DR97_2269	annotation not available	annotation not available	0.900
DR97_287	pncB2	DR97_287	DR97_1553	annotation not available	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	0.900
cinA	DR97_2545	DR97_4321	DR97_2545	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	0.902
cinA	mazG	DR97_4321	DR97_1004	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	0.900
cinA	nadC	DR97_4321	DR97_1703	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family	0.907
cinA	nadD	DR97_4321	DR97_3861	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	annotation not available	0.941
cinA	nudC	DR97_4321	DR97_55	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	annotation not available	0.903
cinA	pncB2	DR97_4321	DR97_1553	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	0.916
cinA	surE	DR97_4321	DR97_4314	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.904
mazG	DR97_2545	DR97_1004	DR97_2545	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	0.903
mazG	cinA	DR97_1004	DR97_4321	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	16,7 kDa protein in recA 5’region; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family	0.900
mazG	nadC	DR97_1004	DR97_1703	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family	0.903

page 1 of 4

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2019

Credits

Access

Info

About