node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1574 | DR97_1576 | DR97_1574 | DR97_1576 | annotation not available | annotation not available | 0.731 |
DR97_1574 | DR97_1577 | DR97_1574 | DR97_1577 | annotation not available | Putative cob(i)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family | 0.712 |
DR97_1574 | panE | DR97_1574 | DR97_1575 | annotation not available | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 0.806 |
DR97_1576 | DR97_1574 | DR97_1576 | DR97_1574 | annotation not available | annotation not available | 0.731 |
DR97_1576 | DR97_1577 | DR97_1576 | DR97_1577 | annotation not available | Putative cob(i)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family | 0.894 |
DR97_1576 | panE | DR97_1576 | DR97_1575 | annotation not available | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 0.800 |
DR97_1577 | DR97_1574 | DR97_1577 | DR97_1574 | Putative cob(i)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family | annotation not available | 0.712 |
DR97_1577 | DR97_1576 | DR97_1577 | DR97_1576 | Putative cob(i)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family | annotation not available | 0.894 |
DR97_1577 | panE | DR97_1577 | DR97_1575 | Putative cob(i)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 0.777 |
PanE | coaBC | DR97_134 | DR97_2691 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine | 0.619 |
PanE | ilvC | DR97_134 | DR97_2036 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate | 0.681 |
PanE | panB1 | DR97_134 | DR97_291 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate | 0.969 |
PanE | panB2 | DR97_134 | DR97_2072 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate | 0.962 |
PanE | panC | DR97_134 | DR97_2073 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate | 0.947 |
PanE | panD | DR97_134 | DR97_2074 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine | 0.815 |
PanE | panE | DR97_134 | DR97_1575 | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 0.851 |
coaBC | PanE | DR97_2691 | DR97_134 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine | 2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid | 0.619 |
coaBC | panB1 | DR97_2691 | DR97_291 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate | 0.587 |
coaBC | panB2 | DR97_2691 | DR97_2072 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate | 0.733 |
coaBC | panC | DR97_2691 | DR97_2073 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate | 0.932 |