node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1862 | ileS | DR97_1862 | DR97_1864 | annotation not available | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | 0.969 |
DR97_1862 | lspA | DR97_1862 | DR97_1863 | annotation not available | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.968 |
DR97_1862 | mviN | DR97_1862 | DR97_1866 | annotation not available | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.698 |
DR97_1862 | ribF | DR97_1862 | DR97_1865 | annotation not available | Bifunctional riboflavin kinase/fmn adenylyltransferase; Belongs to the ribF family | 0.866 |
DR97_491 | lepB | DR97_491 | DR97_1215 | Putative signal peptidase; Belongs to the peptidase S26 family | Signal peptidase i; Belongs to the peptidase S26 family | 0.820 |
DR97_491 | lspA | DR97_491 | DR97_1863 | Putative signal peptidase; Belongs to the peptidase S26 family | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.896 |
ileS | DR97_1862 | DR97_1864 | DR97_1862 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | annotation not available | 0.969 |
ileS | lspA | DR97_1864 | DR97_1863 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.977 |
ileS | mviN | DR97_1864 | DR97_1866 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.724 |
ileS | ribF | DR97_1864 | DR97_1865 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Bifunctional riboflavin kinase/fmn adenylyltransferase; Belongs to the ribF family | 0.970 |
lepB | DR97_491 | DR97_1215 | DR97_491 | Signal peptidase i; Belongs to the peptidase S26 family | Putative signal peptidase; Belongs to the peptidase S26 family | 0.820 |
lepB | lgt | DR97_1215 | DR97_3307 | Signal peptidase i; Belongs to the peptidase S26 family | Phosphatidylglycerol---prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins | 0.586 |
lepB | lspA | DR97_1215 | DR97_1863 | Signal peptidase i; Belongs to the peptidase S26 family | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.970 |
lgt | lepB | DR97_3307 | DR97_1215 | Phosphatidylglycerol---prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins | Signal peptidase i; Belongs to the peptidase S26 family | 0.586 |
lgt | lnt | DR97_3307 | DR97_3881 | Phosphatidylglycerol---prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins | Apolipoprotein n-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation | 0.940 |
lgt | lspA | DR97_3307 | DR97_1863 | Phosphatidylglycerol---prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.957 |
lgt | mviN | DR97_3307 | DR97_1866 | Phosphatidylglycerol---prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.437 |
lnt | lgt | DR97_3881 | DR97_3307 | Apolipoprotein n-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation | Phosphatidylglycerol---prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins | 0.940 |
lnt | lolA | DR97_3881 | DR97_5348 | Apolipoprotein n-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation | Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) | 0.945 |
lnt | lolB | DR97_3881 | DR97_1977 | Apolipoprotein n-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation | Outer membrane lipoprotein lolb; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein | 0.929 |