node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1862 | ileS | DR97_1862 | DR97_1864 | annotation not available | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | 0.969 |
DR97_1862 | lspA | DR97_1862 | DR97_1863 | annotation not available | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.968 |
DR97_1862 | mviN | DR97_1862 | DR97_1866 | annotation not available | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.698 |
DR97_1862 | ribF | DR97_1862 | DR97_1865 | annotation not available | Bifunctional riboflavin kinase/fmn adenylyltransferase; Belongs to the ribF family | 0.866 |
bioB | mrdB | DR97_3468 | DR97_3865 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism | Rod shape determining protein roda; Peptidoglycan polymerase that is essential for cell wall elongation | 0.518 |
bioB | mviN | DR97_3468 | DR97_1866 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.818 |
cysS | ileS | DR97_91 | DR97_1864 | Cysteinyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | 0.941 |
cysS | mviN | DR97_91 | DR97_1866 | Cysteinyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.727 |
ftsW | lspA | DR97_1591 | DR97_1863 | Cell division protein ftsw; Peptidoglycan polymerase that is essential for cell division | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.759 |
ftsW | mrdA | DR97_1591 | DR97_3864 | Cell division protein ftsw; Peptidoglycan polymerase that is essential for cell division | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall | 0.893 |
ftsW | mrdB | DR97_1591 | DR97_3865 | Cell division protein ftsw; Peptidoglycan polymerase that is essential for cell division | Rod shape determining protein roda; Peptidoglycan polymerase that is essential for cell wall elongation | 0.543 |
ftsW | murF | DR97_1591 | DR97_1594 | Cell division protein ftsw; Peptidoglycan polymerase that is essential for cell division | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | 0.997 |
ftsW | mviN | DR97_1591 | DR97_1866 | Cell division protein ftsw; Peptidoglycan polymerase that is essential for cell division | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.958 |
ileS | DR97_1862 | DR97_1864 | DR97_1862 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | annotation not available | 0.969 |
ileS | cysS | DR97_1864 | DR97_91 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Cysteinyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family | 0.941 |
ileS | lspA | DR97_1864 | DR97_1863 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | 0.977 |
ileS | mviN | DR97_1864 | DR97_1866 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Putative virulence factor, membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.724 |
ileS | ribF | DR97_1864 | DR97_1865 | Isoleucyl-trna synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) | Bifunctional riboflavin kinase/fmn adenylyltransferase; Belongs to the ribF family | 0.970 |
lspA | DR97_1862 | DR97_1863 | DR97_1862 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | annotation not available | 0.968 |
lspA | ftsW | DR97_1863 | DR97_1591 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins | Cell division protein ftsw; Peptidoglycan polymerase that is essential for cell division | 0.759 |