rtcA protein (Pseudomonas aeruginosa) - STRING interaction network

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rtcA

RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (341 aa)

Predicted Functional Partners:

rtcB

0.990

rtcR

0.967

ycgL

0.922

ksgA

0.828

rpsD

0.821

DR97_1887

0.759

DR97_2850

0.730

DR97_5311

0.715

rplJ

0.714

guaA

0.634

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_1887	DR97_2850	DR97_1887	DR97_2850	annotation not available	annotation not available	0.683
DR97_1887	DR97_5311	DR97_1887	DR97_5311	annotation not available	annotation not available	0.608
DR97_1887	rtcA	DR97_1887	DR97_1890	annotation not available	RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing	0.759
DR97_1887	rtcB	DR97_1887	DR97_1888	annotation not available	annotation not available	0.932
DR97_1887	rtcR	DR97_1887	DR97_1885	annotation not available	annotation not available	0.494
DR97_1887	ycgL	DR97_1887	DR97_1889	annotation not available	annotation not available	0.870
DR97_2850	DR97_1887	DR97_2850	DR97_1887	annotation not available	annotation not available	0.683
DR97_2850	rtcA	DR97_2850	DR97_1890	annotation not available	RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing	0.730
DR97_2850	rtcR	DR97_2850	DR97_1885	annotation not available	annotation not available	0.748
DR97_2850	ycgL	DR97_2850	DR97_1889	annotation not available	annotation not available	0.653
DR97_5311	DR97_1887	DR97_5311	DR97_1887	annotation not available	annotation not available	0.608
DR97_5311	rtcA	DR97_5311	DR97_1890	annotation not available	RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing	0.715
DR97_5311	rtcR	DR97_5311	DR97_1885	annotation not available	annotation not available	0.647
DR97_5311	ycgL	DR97_5311	DR97_1889	annotation not available	annotation not available	0.582
guaA	ksgA	DR97_4101	DR97_3561	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	0.592
guaA	rplJ	DR97_4101	DR97_3639	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	0.470
guaA	rtcA	DR97_4101	DR97_1890	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing	0.634
ksgA	guaA	DR97_3561	DR97_4101	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.592
ksgA	rplJ	DR97_3561	DR97_3639	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	0.822
ksgA	rpsD	DR97_3561	DR97_3672	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	0.886

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