STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phuRUncharacterized protein; tonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein (764 aa)    
Predicted Functional Partners:
PhuS
annotation not available
  
  
 0.977
hmuV
Iron complex transport system atp-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
  
  
 0.968
PhuW
Hypothetical protein; Uncharacterized protein
  
  
 0.939
pigA
Heme oxygenase (biliverdin-ix-beta and delta-forming); Involved in heme degradation. Catalyzes the degradation of heme to biliverdin, with the release of iron. Forms biliverdin delta (70%) and beta (30%)
 
  
 0.926
PhuU
Iron complex transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
 
  
 0.912
phuT
annotation not available
 
  
 0.898
hasA
annotation not available
      
 0.854
DR97_1693
Outer membrane receptor for iron transport; tonB-siderophor: TonB-dependent siderophore receptor family protein
 
 
 0.781
pvdS
Rna polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily
  
  
 0.767
fptA
Outer-membrane receptor for ferric coprogen and ferric-rhodotorulic acid; High-affinity outer membrane receptor required for the transport of Fe(3+)-pyochelin
  
  
 0.706
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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