STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
acsA2Acetyl-coa synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (645 aa)    
Predicted Functional Partners:
ackA
Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
   
 
 0.988
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions
  
 
 0.988
gltA
Type ii citrate synthase; cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family
  
 0.972
prpC
2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family
  
 0.971
Pcd
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family
  
 0.950
glcB
Malate synthase g; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA
   
 0.949
DR97_3845
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family
  
 0.949
exaC
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family
  
 0.949
pauA
annotation not available
 
 
 0.949
PchA
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family
  
 0.948
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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