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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YfjFRnfh ubiquitin family protein; Belongs to the UPF0125 (RnfH) family (101 aa)    
Predicted Functional Partners:
ratA
Polyketide cyclase / dehydrase and lipid transport family protein; Toxic component of a type II toxin-antitoxin (TA) system. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes. Its antitoxin is unknown (By similarity)
 
  
 0.992
rnfB
Na+-translocating ferredoxin:nad+ oxidoreductase subunit b; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane
 
   
 0.700
PerM
Hypothetical protein; Transport of quorum-sensing signal protein
      
 0.683
smpB
Ssra-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.620
DR97_2660
annotation not available
  
     0.604
rnfG
Na+-translocating ferredoxin:nad+ oxidoreductase subunit g; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane
 
   
 0.478
guaA
Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP
       0.459
rnfC
Na+-translocating ferredoxin:nad+ oxidoreductase subunit c; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane
 
   
 0.455
rnfE
Na+-translocating ferredoxin:nad+ oxidoreductase subunit e; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane
 
   
 0.409
rnfD
Na+-translocating ferredoxin:nad+ oxidoreductase subunit d; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane
 
   
 0.406
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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