node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_2183 | DR97_5924 | DR97_2183 | DR97_5924 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | annotation not available | 0.510 |
DR97_2183 | DR97_6021 | DR97_2183 | DR97_6021 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | annotation not available | 0.532 |
DR97_2183 | amiA | DR97_2183 | DR97_2916 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | annotation not available | 0.419 |
DR97_2183 | cntI | DR97_2183 | DR97_2184 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | Eama-like transporter family protein; Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the export of pseudopaline (By similarity). Essential for iron acquisition during the interaction with airway mucus secretions (AMS) | 0.526 |
DR97_2183 | cntL | DR97_2183 | DR97_2186 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | Histidine 2-aminobutanoyltransferase; Catalyzes the nucleophilic attack of one alpha-aminobutanoate moiety from SAM onto L-histidine to produce the intermediate (2S)-2- amino-4- Functions in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to Pseudomonas virulence. Appears to be specific for L-histidine as substrate | 0.495 |
DR97_2183 | cntM | DR97_2183 | DR97_2185 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | Staphylopine/pseudopaline/yersinopine synthase; Catalyzes the NAD(P)H-dependent reductive condensation of alpha-ketoglutarate to the intermediate formed by the adjacently encoded enzyme PA4836, namely (2S)-2-amino-4- pseudopaline. This is the last step in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to Pseudomonas virulence. Can use neither pyruvate nor oxaloacetate in place of alpha-ketoglutarate Is [...] | 0.535 |
DR97_2183 | hasR | DR97_2183 | DR97_4513 | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | annotation not available | 0.518 |
DR97_2188 | cntI | DR97_2188 | DR97_2184 | annotation not available | Eama-like transporter family protein; Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the export of pseudopaline (By similarity). Essential for iron acquisition during the interaction with airway mucus secretions (AMS) | 0.628 |
DR97_2188 | cntL | DR97_2188 | DR97_2186 | annotation not available | Histidine 2-aminobutanoyltransferase; Catalyzes the nucleophilic attack of one alpha-aminobutanoate moiety from SAM onto L-histidine to produce the intermediate (2S)-2- amino-4- Functions in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to Pseudomonas virulence. Appears to be specific for L-histidine as substrate | 0.592 |
DR97_2188 | cntM | DR97_2188 | DR97_2185 | annotation not available | Staphylopine/pseudopaline/yersinopine synthase; Catalyzes the NAD(P)H-dependent reductive condensation of alpha-ketoglutarate to the intermediate formed by the adjacently encoded enzyme PA4836, namely (2S)-2-amino-4- pseudopaline. This is the last step in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to Pseudomonas virulence. Can use neither pyruvate nor oxaloacetate in place of alpha-ketoglutarate Is [...] | 0.558 |
DR97_2188 | cntO | DR97_2188 | DR97_2187 | annotation not available | Tonb-dependent siderophore receptor family protein; Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the import of pseudopaline-metal complexes | 0.765 |
DR97_5924 | DR97_2183 | DR97_5924 | DR97_2183 | annotation not available | Hemolysin-III related; hlyIII: channel , hemolysin III family protein | 0.510 |
DR97_5924 | DR97_6021 | DR97_5924 | DR97_6021 | annotation not available | annotation not available | 0.446 |
DR97_5924 | DR97_6022 | DR97_5924 | DR97_6022 | annotation not available | annotation not available | 0.417 |
DR97_5924 | amiA | DR97_5924 | DR97_2916 | annotation not available | annotation not available | 0.637 |
DR97_5924 | cntI | DR97_5924 | DR97_2184 | annotation not available | Eama-like transporter family protein; Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the export of pseudopaline (By similarity). Essential for iron acquisition during the interaction with airway mucus secretions (AMS) | 0.580 |
DR97_5924 | cntL | DR97_5924 | DR97_2186 | annotation not available | Histidine 2-aminobutanoyltransferase; Catalyzes the nucleophilic attack of one alpha-aminobutanoate moiety from SAM onto L-histidine to produce the intermediate (2S)-2- amino-4- Functions in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to Pseudomonas virulence. Appears to be specific for L-histidine as substrate | 0.613 |
DR97_5924 | cntM | DR97_5924 | DR97_2185 | annotation not available | Staphylopine/pseudopaline/yersinopine synthase; Catalyzes the NAD(P)H-dependent reductive condensation of alpha-ketoglutarate to the intermediate formed by the adjacently encoded enzyme PA4836, namely (2S)-2-amino-4- pseudopaline. This is the last step in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to Pseudomonas virulence. Can use neither pyruvate nor oxaloacetate in place of alpha-ketoglutarate Is [...] | 0.548 |
DR97_5924 | cntO | DR97_5924 | DR97_2187 | annotation not available | Tonb-dependent siderophore receptor family protein; Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the import of pseudopaline-metal complexes | 0.579 |
DR97_5924 | hasR | DR97_5924 | DR97_4513 | annotation not available | annotation not available | 0.440 |