node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fis | polA | DR97_2204 | DR97_2871 | Fis family transcriptional regulator, factor for inversion stimulation protein; Belongs to the transcriptional regulatory Fis family | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.558 |
Fis | rpsI | DR97_2204 | DR97_1610 | Fis family transcriptional regulator, factor for inversion stimulation protein; Belongs to the transcriptional regulatory Fis family | Small subunit ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family | 0.594 |
Fis | tig | DR97_2204 | DR97_80 | Fis family transcriptional regulator, factor for inversion stimulation protein; Belongs to the transcriptional regulatory Fis family | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase | 0.441 |
Fis | typA | DR97_2204 | DR97_2471 | Fis family transcriptional regulator, factor for inversion stimulation protein; Belongs to the transcriptional regulatory Fis family | typA_BipA: GTP-binding protein TypA/BipA | 0.724 |
cgtA | engA | DR97_1870 | DR97_4070 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.922 |
cgtA | guaA | DR97_1870 | DR97_4101 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | 0.727 |
cgtA | polA | DR97_1870 | DR97_2871 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.705 |
cgtA | rpsI | DR97_1870 | DR97_1610 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Small subunit ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family | 0.746 |
cgtA | thiI | DR97_1870 | DR97_2472 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Thiamine biosynthesis protein thii; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS | 0.531 |
cgtA | tig | DR97_1870 | DR97_80 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase | 0.470 |
cgtA | tsf | DR97_1870 | DR97_4284 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Translation elongation factor ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) | 0.720 |
cgtA | typA | DR97_1870 | DR97_2471 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | typA_BipA: GTP-binding protein TypA/BipA | 0.615 |
cysN/C | typA | DR97_1620 | DR97_2471 | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity | typA_BipA: GTP-binding protein TypA/BipA | 0.691 |
engA | cgtA | DR97_4070 | DR97_1870 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 0.922 |
engA | polA | DR97_4070 | DR97_2871 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.535 |
engA | rpsI | DR97_4070 | DR97_1610 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Small subunit ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family | 0.555 |
engA | tig | DR97_4070 | DR97_80 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase | 0.627 |
engA | tsf | DR97_4070 | DR97_4284 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Translation elongation factor ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) | 0.777 |
engA | typA | DR97_4070 | DR97_2471 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | typA_BipA: GTP-binding protein TypA/BipA | 0.662 |
guaA | cgtA | DR97_4101 | DR97_1870 | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 0.727 |