node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_2565 | DR97_2567 | DR97_2565 | DR97_2567 | annotation not available | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | 0.528 |
DR97_2565 | rimK | DR97_2565 | DR97_2566 | annotation not available | rimK_fam: alpha-L-glutamate ligases, RimK family protein; Belongs to the RimK family | 0.992 |
DR97_2567 | DR97_2565 | DR97_2567 | DR97_2565 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | annotation not available | 0.528 |
DR97_2567 | DR97_2857 | DR97_2567 | DR97_2857 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | annotation not available | 0.570 |
DR97_2567 | ampC | DR97_2567 | DR97_3761 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | Beta-lactamase class c pdc; Belongs to the class-C beta-lactamase family | 0.852 |
DR97_2567 | ampD | DR97_2567 | DR97_1701 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | annotation not available | 0.522 |
DR97_2567 | anmK | DR97_2567 | DR97_3619 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | Anhydro-n-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P (By similarity). Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. Contributes to intrinsic fosfomycin resistance in P.aeruginosa | 0.617 |
DR97_2567 | guaA | DR97_2567 | DR97_4101 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | 0.593 |
DR97_2567 | metG | DR97_2567 | DR97_4439 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | Methionyl-trna synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation | 0.503 |
DR97_2567 | mpl | DR97_2567 | DR97_3847 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | Udp-n-acetylmuramate: l-alanyl-gamma-d-glutamyl-meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate | 0.583 |
DR97_2567 | nagZ | DR97_2567 | DR97_4932 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | Beta-n-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides (By similarity). Contributes to intrinsic fosfomycin resistance in P.aeruginosa | 0.744 |
DR97_2567 | rimK | DR97_2567 | DR97_2566 | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | rimK_fam: alpha-L-glutamate ligases, RimK family protein; Belongs to the RimK family | 0.610 |
DR97_2857 | DR97_2567 | DR97_2857 | DR97_2567 | annotation not available | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | 0.570 |
DR97_2857 | metG | DR97_2857 | DR97_4439 | annotation not available | Methionyl-trna synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation | 0.434 |
ampC | DR97_2567 | DR97_3761 | DR97_2567 | Beta-lactamase class c pdc; Belongs to the class-C beta-lactamase family | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | 0.852 |
ampC | ampD | DR97_3761 | DR97_1701 | Beta-lactamase class c pdc; Belongs to the class-C beta-lactamase family | annotation not available | 0.928 |
ampC | mpl | DR97_3761 | DR97_3847 | Beta-lactamase class c pdc; Belongs to the class-C beta-lactamase family | Udp-n-acetylmuramate: l-alanyl-gamma-d-glutamyl-meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate | 0.785 |
ampC | nagZ | DR97_3761 | DR97_4932 | Beta-lactamase class c pdc; Belongs to the class-C beta-lactamase family | Beta-n-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides (By similarity). Contributes to intrinsic fosfomycin resistance in P.aeruginosa | 0.901 |
ampD | DR97_2567 | DR97_1701 | DR97_2567 | annotation not available | Muramoyltetrapeptide carboxypeptidase; Releases the terminal D-alanine residue from the cytoplasmic disaccharide-tetrapeptide GlcNAc-MurNAc-L-Ala-gamma-D-Glu-meso-Dap-D- Ala, which is a murein turnover product. Probably also act on free tetrapetide. May be involved in murein recycling | 0.522 |
ampD | ampC | DR97_1701 | DR97_3761 | annotation not available | Beta-lactamase class c pdc; Belongs to the class-C beta-lactamase family | 0.928 |